2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-137236
    6β-Hydroxy metandienone
    6β-Hydroxy metandienone is an anabolic androgenic steroid metabolite of Metandienone.
    6β-Hydroxy metandienone
  • HY-143951S
    Disulfiram impurity 1-d10
    Disulfiram impurity 1-d10 is the deuterium labeled Disulfiram impurity 1[1].
    Disulfiram impurity 1-d<sub>10</sub>
  • HY-B0601R
    Tafluprost acid (Standard)
    		Chemical
    Tectoquinone (Standard) is the analytical standard of Tectoquinone. This product is intended for research and analytical applications. Tectoquinone (2-Methylanthraquinone) is a SARSCoV-2 main protease inhibitor against COVID-19. Tectoquinone exhibits strong mosquito larvicidal activity with the LC50 values of 3.3 and 5.4 μg/ml against A. aegypti and A. albopictus in 24 h, respectively.
    Tafluprost acid (Standard)
  • HY-W740380
    21-Carboxylic acid triamcinolone acetonide
    21-Carboxylic acid triamcinolone acetonide is a metabolite produced in the body after oral administration of [14C]-triamcinolone acetonide.
    21-Carboxylic acid triamcinolone acetonide
  • HY-B0300S
    Penicillamine-d3
    Penicillamine-d3 is the deuterium labeled Penicillamine. Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
    Penicillamine-d<sub>3</sub>
  • HY-B0652R
    Etonogestrel (Standard)
    Etonogestrel (Standard) is the analytical standard of Etonogestrel. This product is intended for research and analytical applications. Etonogestrel (3-Oxodesogestrel), a biologically active metabolite of progestin Desogestrel, binds with high affinity to progesterone receptors and estrogen receptors in the target organs. Etonogestrel induce FKBP51 mRNA and protein expression in cultured human endometrial stromal cells (HESCs).
    Etonogestrel (Standard)
  • HY-113289R
    Brassicasterol (Standard)
    L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective.
    Brassicasterol (Standard)
  • HY-W010593R
    Ethylenethiourea (Standard)
    Ethylenethiourea (Standard) is the analytical standard of Ethylenethiourea. This product is intended for research and analytical applications. Ethylenethiourea is a degradation product of the ethylenebisthiocarbamate group of fungicides. Ethylenethiourea is tumorigenic and teratogenic. Ethylenethiourea is orally active.
    Ethylenethiourea (Standard)
  • HY-143974S
    Imiquimod impurity 1-d6
    Imiquimod impurity 1-d6 is the deuterium labeled Imiquimod impurity 1[1].
    Imiquimod impurity 1-d<sub>6</sub>
  • HY-101200R
    Linsidomine (hydrochloride) (Standard)
    		Modulator
    Linsidomine (hydrochloride) (Standard) is the analytical standard of Linsidomine (hydrochloride). This product is intended for research and analytical applications. SIN-1 (chloride) is the active metabolite of molsidomine. SIN-1 (chloride) exhibits potent vasorelaxant effect and inhibition of platelet aggregation. SIN-1 (chloride) decreases myocardial necrosis and reperfusion-induced endothelial dysfunction in models of myocardial ischemia-reperfusion.
    Linsidomine (hydrochloride) (Standard)
  • HY-101108R
    Tazarotenic acid (Standard)
    Deoxycholic acid (Standard) is the analytical standard of Deoxycholic acid. This product is intended for research and analytical applications. Deoxycholic acid (cholanoic acid), a bile acid, is a by-product of intestinal metabolism, that activates the G protein-coupled bile acid receptorTGR5.
    Tazarotenic acid (Standard)
  • HY-135373
    Desfluoro-atorvastatin
    Desfluoro-atorvastatin is an impurity of Atorvastatin. Atorvastatin is an orally active 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, has the ability to effectively decrease blood lipids.
    Desfluoro-atorvastatin
  • HY-111742
    Bifenazate-diazene
    Bifenazate-diazene is a major degradation product of Bifenazate. Bifenazate is a selective carbazate acaricide and an insecticide.
    Bifenazate-diazene
  • HY-118247
    Ro 14-6113
    Ro 14-6113 is an inactive phenolic metabolite of the "carotenoid" Ro 15-0778, a form of vitamin A.
    Ro 14-6113
  • HY-78846
    2R,4R-Sacubitril
    		98.66%
    2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is approved by the Food and agent Administration for use in combination with valsartan for the treatment of patients with heart failure.
    2R,4R-Sacubitril
  • HY-135334S
    ACP-5862-d4
    ACP-5862-d4 is deuterium labeled ACP-5862. ACP-5862 is a major active, circulating, pyrrolidine ring-opened metabolite of Acalabrutinib with an IC50 of 5.0 nM for Bruton tyrosine kinase (BTK). ACP‐5862 is a weak time‐dependent inactivator of CYP3A4 and CYP2C8. Acalabrutinib is an orally active, irreversible, and highly selective BTK inhibitor, with an IC50 of 3 nM and EC50 of 8 nM[1][2].
    ACP-5862-d<sub>4</sub>
  • HY-129491S
    O-Desmethyl Midostaurin-d5
    O-Desmethyl Midostaurin-d5 is a deuterium labeled O-Desmethyl PKC412. O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism[1].
    O-Desmethyl Midostaurin-d<sub>5</sub>
  • HY-169046
    (±)13,14-DiHDoTrE
    (±)13,14-DiHDoTrE ((±)13,14-DHDT) is an oxylipin and a metabolite of Adrenic acid (HY-W013215).
    (±)13,14-DiHDoTrE
  • HY-138166R
    Rosuvastatin lactone (Standard)
    Rosuvastatin lactone (Standard) is the analytical standard of Rosuvastatin lactone. This product is intended for research and analytical applications. Rosuvastatin lactone is a metabolite of Rosuvastatin (HY-17504A) (HMG-CoA inhibitor).
    Rosuvastatin lactone (Standard)
  • HY-147323R
    Ferulic acid 4-O-sulfate (Standard)
    Ferulic acid 4-O-sulfate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity